Study Indicates That Teeth Can Regenerate & Repair Itself; "Tideglusib" Key To Stimulate Repair?

By Carrie Winters - 10 Jan '17 16:17PM
  • 'Teeth Regeneration'
  • (Photo : Andrew Burton/Getty Images) A new method has been tested in mice which indicate that teeth may regenerate on their own in the future. A drug named Tideglusib may help in stimulating teeth for it to be able to fix decay.

A new method has been tested in mice which indicate that teeth may regenerate on their own in the future. A drug named Tideglusib may help in stimulating teeth for it to be able to fix decay.

According to a report, this study is still in the laboratory stage but it may work someday. Lead researcher, Paul Sharpe explains that teeth have limited capabilities to repair on its own using stem cells. He adds that natural repair is enhanced through the help of Tideglusib.

The restoration of the tooth using its own stem cells means that the tooth will be back to its natural structure. This new field in dentistry is called the regenerative endodontics. It is a field focused in saving teeth.

A report also indicates that this way of regenerating teeth uses the activation of stem cells which happens to be the soft pulp at the center. Tideglusib enhances the process by rebuilding cavities which extends from the surface to the root.

The laboratory test used mice and it showed that by soaking a biodegradable sponge into the drug then filled the decayed tooth with it, the tooth gradually rebuilt itself. Scientists had discovered that the tooth of the mouse being tested has finally regained its natural structure after it underwent the process.

Instead of filling the decayed tooth with cement, this process may be better since it brings back the tooth to its natural form. This way there will not be any other material being placed into the tooth with the decay.

Meanwhile, it is indicated in the report that the teeth can already repair on its own with the production of dentin. The dentin is enough for the teeth to fix small cracks on its own. However, when the cavity is larger, this is the time that dentists do add more into it so to fix the teeth. This study may be helpful in the future for repairing ones teeth.

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